261Comparative in vitro Activity of Sitafloxacin and Other Antibiotics Against Clinical Isolates of Carbapenem-Resistant Acinetobacter baumannii and Carbapenem-Resistant Pseudomonas aeruginosa by Disk Diffusion Method
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Prevalence of IMP and SPM Genes in Clinical Isolatesof Carbapenem Resistant Acinetobacter baumannii in Educational Hospitals of Sari, Iran
Background and purpose: Acinetobacter Baumannii is an opportunistic bacterium, which is considered as a concern in hospitals throughout the world due to high antibiotic resistance rate. The aim of this study was to investigate the prevalence of carbapenem resistance genes in clinical isolates of this bacterium. Materials and methods: In this study, 100 clinical isolates of Acinetobacter Bauman...
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Introduction: The major resistance mechanisms of Pseudomonas aeruginosa to fluoroquinolones and carbapenems are associated with the mutations in the genes gyrA and oprD encoding type II topoisomerases (DNA gyrase) and OprD porin, respectively. Method: In this cross-sectional study, sixty five clinical samples were collected from patients hospitalized in Al-Zahra Hospital of Isfahan, Iran. Susce...
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Introduction: Acinetobacter baumannii, a known causative agent of nosocomial infections, is one of the highly antibiotic-resistant gram-negative bacilli. Carbapenem-resistant Acinetobacter isolates are increasingly reported worldwide. Carbapenems such as imipenem and meropenem are efficient antimicrobial agents commonly used for the treatment of infections caused by multi- resistant A. baumanni...
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Objective(s):Antibiotic resistance in Acinetobacter baumannii and outbreaks caused by this organism have been reported from several areas of the world. The present study aimed at determining the antibiotic susceptibility profiles and the distribution of OXA-type beta-lactamases among Iranian Acinetobacter baumannii isolates from Qom of Iran. Materials and Methods: For this study, 108 non-duplic...
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Background & objective: Beta-lactam antibiotics resistance specifically Imipenem and Meropenem, the last choices of treatment, causes fatal events in patients with P.aeruginosa infection. The aim of this study was to detect the VIM and IMP of metallo-beta-lactamase genes in 103 isolates of P. aeruginosa in two Iranian hospitals. <strong...
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